Yazar "Agalar, Canan" için listeleme
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Antimicrobial activity of cefazolin-impregnated mesh grafts
Kilic, Dilek; Agalar, Canan; Ozturk, Eylem; Denkbas, Emir B.; Cime, Abdullah; Agalar, Fatih (Blackwell Publishing, 2007)Background: The aim of this study is the preparation and characterization of cefazolin-impregnated meshes (Surgipro; Tyco Healthcare USSC, Norwalk, CT, USA) to be used as antimicrobial devices. Method: During the impregnation, ... -
The Effect of Hypothermia on Splanchnic Flows and Lung in a Two-Hit Hemorrhagic Shock Model
Deniz, Turgut; Agalar, Canan; Agalar, Fatih; Comu, Faruk M.; Caglayan, Osman; Alpay, Yesim; Saygun, Oral (Academic Press Inc Elsevier Science, 2010)Background. To evaluate the effect of hypothermia on bacterial translocation, splanchnic vascular flow, lung tissue weight, and levels of malondialdehyde (MDA) and nitric oxide (NO) in a two-hit model of hemorrhagic shock. ... -
The Effect of Simvastatin on Pulmonary Damage in Experimental Peritonitis in Rats
Altunal, Cetin; Agalar, Fatih; Agalar, Canan; Daphan, Cagatay; Saygun, Oral; Aydinuraz, Kuzey; Dom, Sedat (Springer India, 2015)Statins are widely used in the treatment of hyperlipidemia, as they inhibit cholesterol synthesis. They also have anti-inflammatory, antioxidant, immunomodulatory, and positive endothelial-functional effects. It is ... -
The effect of thymoquinone coating on adhesive properties of polypropylene mesh
Aydin, Oktay; Aydinuraz, Kuzey; Agalar, Fatih; Sahiner, I. Tayfun; Agalar, Canan; Bayram, Cem; Atasoy, Pinar (Bmc, 2017)Background: An incisional hernia is a common complication following abdominal surgery. Polypropylene mesh is frequently used in the repair of such defects and has nearly become the standard surgical treatment modality. ... -
Effects of granulocyte-colony stimulating factor on peritoneal defense mechanisms and bacterial translocation after administration of systemic chemotherapy in rats
Cerci, Celal; Ergin, Cagri; Eroglu, Erol; Agalar, Canan; Agalar, Fatih; Cerci, Sureyya; Bulbul, Mahmut (Baishideng Publishing Group Inc, 2007)AIM: To investigate the effects of granulocyte-colony stimulating factor (G-CSF) on peritoneal defense mechanisms and bacterial translocation after systemic 5-Fluorouracil (5-FU) administration. METHODS: Thirty Wistar ... -
In Vitro S. epidermidis and S. aureus Adherence to Composite and Lightweight Polypropylene Grafts
Aydinuraz, Kuzey; Agalar, Canan; Agalar, Fatih; Ceken, Sabahat; Duruyurek, Nihal; Vural, Tayfun (Academic Press Inc Elsevier Science, 2009)Background. Despite the significant risk of infection, prosthetic graft materials have become indispensable for incisional hernia repair. Composite and lightweight grafts have been developed to overcome adhesion and rigidity. ... -
Inhibition of Staphylococcus epidermidis colonization with fusidic acid-impregnated catheters
Agalar, Canan; Kilic, Dilek; Ceken, Sabahat; Ozdogan, Mehmet; Yasar, Erdem; Ozturk, Eylem; Denkbas, Emir Baki (Sage Publications Ltd, 2007)The aim of this study was the preparation and characterization of fusidic acid-impregnated peripheral catheters. In the first part of the study, in vitro drug release studies were performed, and the effect of fusidic acid ... -
Mild Hypothermia Improves Survival During Hemorrhagic Shock Without Affecting Bacterial Translocation
Deniz, Turgut; Agalar, Canan; Ozdogan, Mehmet; Edremitlioglu, Mustafa; Eryilmaz, Mehmet; Devay, Seda Duygulu; Agalar, Fatih (Taylor & Francis Inc, 2009)Background: Accidental hypothermia in patients with hemorrhagic shock (HS) is associated with increased mortality. However, experimental mild and moderate hypothermia has beneficial effects. The mechanisms for beneficial ... -
Oral carbohydrate solution ameliorates endotoxemia-induced splanchnic ischemia
Deniz, Turgut; Agalar, Canan; Ozdogan, Mehmet; Comu, Faruk; Emirdogan, Mustafa; Taskin, Seda; Agalar, Fatih (Springer, 2007)The purpose of this study was to investigate the effect of oral administration of a simple carbohydrate solution on splanchnic circulation and bacterial translocation in endotoxemia. Group 1 was sham control; group 2 was ... -
Prognostic significance of transforming growth factor-beta-1 in chronic hepatitis C virus infection
Deveci, Ozcan; Agalar, Canan; Demirdal, Tuna; Demirturk, Nese; Yula, Erkan; Tekin, Alicem; Kilic, Dilek (Academic Journals, 2012)Interferon treatment in hepatitis C virus (HCV) infection is expensive and has various adverse effects. Some markers may help in making decision to stop or maintain the treatment. The aim of this study was to evaluate the ... -
Protective Effect of Hypothermia in a Blunt Thoracic Trauma and Hemorrhagic Shock Model
Ulger, Huseyin; Deniz, Turgut; Comu, Faruk; Agalar, Canan; Kisa, Ucler; Agalar, Fatih (Georg Thieme Verlag Kg, 2014)Background The aim of this study was to investigate the effect of volume-controlled hemorrhage and hypothermia on rats with blunt chest trauma, evaluating bacterial translocation (BT), lung tissue malondialdehyde (MDA), ... -
The value of CRP, IL-6, leptin, cortisol, and peritoneal caspase-3 monitoring in the operative strategy of secondary peritonitis
Pehlivanli, Faruk; Agalar, Fatih; Agalar, Canan; Saygun, Oral; Daphan, Cagatay; Aydinuraz, Kuzey; Sahiner, Tayfun (Turkish Assoc Trauma Emergency Surgery, 2011)BACKGROUND We aimed to investigate the impact of C-reactive protein (CRP), interleukin (IL)-6, leptin, cortisol, and caspase-3 on the decision of terminating planned abdominal repair in secondary peritonitis. METHODS Fifteen ...